Minastrin 24 Fe: Uses and Side Effects of Minastrin (Birth Control Pill)

By Miriatu

Minastrin 24 Fe

As the economy of the world gets worse, there are so many uncertainties in life. One is the assurance of growing a family. Thus, many families in a bid to overturn these effects have turn to restrict or reduce the number of children they can have, hence the need for birth control. Birth control should be a decision of both couples. There are many methods or ways that is available to couple to take control of their birth rate, such as the use of condom during unsafe periods, abstinence from sex during unsafe periods, and birth control pills. The use of condoms may be good but condoms are not 100% guarantee as it may burst during sex. Also, if a woman, like some reports stipulate, turn to deprive the husband during her unsafe period from sex, it may degenerate to worse scenario with divorce at the end of the tunnel. So the best alternative is pills. A pill is simple a medication that can be administer (orally, insertion into the vagina or by injection) that acts to prevent the sperm and ova to fuse to form an embryo or prevent the newly form embryo from attaching in the uterus thus, its flus out of the system. One of such pills is Minastrin 24 Fe.

Minastrin 24 Fe is not recommended for people who had a history stroke, heart attack, and blood clots in the arms and legs known as deep vein thrombosis, lungs (pulmonary embolism), or eyes (retinal thrombosis). It should not also be given to those who have certain kinds of severe migraine headaches with numbness, over the age of 35 years, weakness in vision, and heart valve problems or heart rhythm abnormalities that can cause blood clots to form in the heart, an inherited problem which makes their blood to clot more often than normal. Those who are diagnosed with high blood pressure that medicine cannot control, breast cancer or any cancer that is sensitive to female hormones, diabetes with nerve, blood vessel or kidney damage and liver disease, including liver tumors should also not be given this pill.

In a situation where you ever had jaundice (yellowing of the skin or eyes) caused by pregnancy, also called cholestasis of pregnancy, birth control pills may not be a favorite choice. Your health care provider should be informed if ever you have had any of the above conditions (another way of birth control could be recommended by your health care provider).

Functioning and Effectiveness

Minastrin 24 Fe is an oral contraceptive or birth control pill. Oral to mean it’s mode of administration is through the mouth like most tablets, but it works in directed in the uterus of the woman. Contraceptive here means it works for the prevention of pregnancy; avoid unwanted pregnancy or better still, used as a better medium for family planning. If a family does not want more babies, they do not have to avoid sex, but simply resolve to take a simple tablet like Minastrin 24 Fe while having pleasurable sex.

Minastrin 24 Fe contains norethindrone acetate and ethinyl estradiol capsules (estrogens) and ferrous fumarate capsules, which are made up of a progestin. The effectiveness of this medication is that it brings changes in your cervical mucus and uterine lining, which makes it impossible for the passing of sperm into the uterus. This also resulted in the inability for a fertilized egg to attach to the uterus. Thus, Minastrin is applied as means of contraception for the prevention of pregnancy. This medication must be taken according to the doctor’s prescription in order for it to be effective.

Healthcare professionals should advise women to begin taking Minastrin 24 Fe either on the first day of her menstrual period (Day 1 Start) or on the first Sunday after the onset of her menstrual period (Sunday Start). Day 1 Starts during the first cycle of Minastrin 24 Fe use, a patient may be instructed to take one yellow Minastrin 24 Fe capsule daily for 24 non-stop days, and then followed by one maroon capsule daily on days 25 to 28. The administration of Minastrin 24 Fe may also be done following the instructions given on the package at the same time daily or as prescribed by your doctor. Healthcare providers should instruct the subjects to apply a non-hormonal contraceptive as back-up during the first 7 days (if they start taking Minastrin 24 Fe on a day other than the first day of their menstrual cycle).

The possibility of conception and ovulation prior to initiation of medication should also be considered. The patient should start her next and all subsequent 28-day regimens of Minastrin 24 Fe on the same day of the week that she began her first regimen, accompanying the same agenda. She should therefore begin by taking her yellow capsules on the next day after ingestion of the last maroon capsule, irrespective of whether or not a menstrual period is still in progress or has happened. Whenever a future cycle of Minastrin 24 Fe is started later than the day following administration of the last maroon capsule, those affected should consult another method of contraception until they have taken a yellow Minastrin 24 Fe capsule daily for 7 consecutive days. For postpartum women who do not breastfeed or after a second quarterly abortion, begin Minastrin 24 Fe no earlier than one month postpartum due to the increased danger of thromboembolism. Minastrin 24 Fe may be introduced immediately after a first-trimester abortion or miscarriage; if the patient starts Minastrin 24 Fe rapidly; further contraceptive tips are not required. Always talk with your health care provider in case of any doubt.

Also, birth control pills should not be taken if you are over 35 years and smoke, pregnant or suspect you are pregnant, and if you have and any unexplained bleeding from the vagina.

Missed Minastrin dosages may not be harmful if you miss any yellow capsules, especially if you forget the first, the last or few yellow capsules in a pack. Take the capsule as soon as you recall. Also take the next capsule at your normal hour. This means that you may administer two capsules in one day. There is no need to use a back-up birth control method if you have sex. However, seek advice from your doctor before taking any miss dose. Over dosage of Minastrin 24 Fe and ingestion by children may lead to increased risk of the known side effects. Report any overdose to your healthcare provider.

Uses of Minastrin 24 Fe

Minastrin 24 Fe is use as an oral contraceptive. It uses may also include other purposes not discussed in this article. You should talk with your healthcare provider about the various uses of Minastrin 24 Fe.

Remember that your maximum benefits or your chance for you to prevent pregnancy depends on how well you keep to the doctor’s advices and recommendations.

Side Effects Minastrin 24 Fe

Minastrin may have severe or mild side effects. The resulting side effects may depend on other medications the patient might be receiving. These undesirable reactions may be grouped into two main categories thus:

In a situation where any of these effects of Minastrin Fe persist or worsen, contact your health care provider or pharmacist immediately.

Major Side Effects of Minastrin 24 Fe

This includes all the known serious Minastrin side effects that may occur during its administration. Thus, if you suspects or notice any of these Minastrin side effects, you should immediately inform you’re your healthcare provider or emergency help services for and emergency help.

  • Abdominal or stomach pain
  • absent, missed, or irregular menstrual periods
  • anxiety
  • change in vision
  • changes in skin color
  • dark urine
  • diarrhea
  • dizziness or lightheadedness
  • depression
  • fainting
  • fast heartbeat
  • loss of appetite
  • medium to heavy, irregular vaginal bleeding between regular monthly periods, which may require the use of a pad or a tampon
  • nausea and vomiting
  • rash
  • sudden shortness of breath or troubled breathing
  • sweating
  • unusual tiredness or weakness
  • vomiting of blood
  • redness of the skin
  • severe headaches of sudden onset
  • chest pain or discomfort
  • chills
  • clay-colored stools
  • constipation
  • cough
  • fever
  • headache
  • hives or welts
  • itching skin
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • pain or discomfort in the arms, jaw, back, or neck
  • pain, tenderness, or swelling of the foot or leg
  • sudden loss of coordination or slurred speech
  • sudden onset of shortness of breath for no apparent reason
  • pains in the chest, groin, or legs, especially in the calves of the legs
  • pounding in the ears


Minor Side Effects Minastrin 24 Fe

These are also other side effects of Minastrin that may be seen in some subjects. Most of these effects need no medical help as they normally disappear as the body become use to the drug. However, some may persist, requiring the attention of a healthcare professional to help treat them. Your healthcare provider may also be able to advice you about various ways to prevent or reduce some of these side effects. If any of the following side effects persist, or are troublesome, you should consult with a healthcare professional:

  • discouragement
  • feeling sad or empty
  • irritability
  • itching of the vagina or outside genitals
  • loss of interest or pleasure
  • pain during sexual intercourse
  • thick, white curd-like vaginal discharge without odor or with mild odor
  • Abdominal or stomach cramps
  • bloating
  • blotchy spots on the exposed skin
  • breast enlargement or tenderness
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • trouble wearing contact lenses


While this may not be a complete list of all the possible side effects Minastrin 24 Fe, you should check with your healthcare provider about the various unwanted reactions of this drug that may be consistent with your medical record. You should also report all side effects which you may notice during treatment to your healthcare provider and in case of doubt, don’t hesitate to talk it out with him.

Half-life of Minastrin 24 Fe

This is the time taken for the plasma concentration of Minastrin and/or its metabolites to reduce to half its original vale. Norethindrone and ethinyl estradiol, both components of Minastrin 24 Fe are eliminated from the body in both urine and feces, mainly as metabolites. These two components are said to have the similar plasma clearance values (approximately 0.4 L/hr/kg). At steady-state, the elimination half-life of norethindrone is about 8 hours while that for ethinyl estradiol is about 14 hours following administration of Minastrin 24 Fe tablets.

Storage and Handling Conditions of Minastrin 24 Fe

Store at room temperature, 25º C (77º F) and away from high temperatures and direct sun light. Store blister card in the wallet provided in the carton when not in use. You may grind, chew or swallowed whole. Capsules must be taken in the order directed on the blister pack. Capsules must not be taken or skipped at intervals going beyond 24 hours. Minastrin 24 Fe may be administered without regard to meals. Do not used when found to have expired and depose following best environmental practices. Keep all medicines out of the reach of children and pets.

Use in Specific Populations


Studies involving the use of Minastrin 24 during pregnancy show no significant change (there was little or no increase) in the risk of birth defects. Also, other epidemiologic studies and meta-analyses following the use of low COCs before pregnancy or during the early stages of pregnancy did not show or indicate any change in the risk of genital or non-genital birth defects (consisting of limb reduction defects and cardiac anomalies). However, care must be taken not to use COCs to treat habitual or threatened abortion during pregnancy and also not to use the administration of COCs to induce withdrawal bleeding as a test for pregnancy.

Nursing/breastfeeding women

Nursing or breastfeeding women should be advice not to use Minastrin 24 (they can use other types of contraception) during the lactation period as COCs can reduce the quality and quantity of milk production. Some amounts of oral contraceptive steroids or its metabolites, though small has been identified in human breast milk. This may not occur when Minastrin 24 use is initiated after the woman had already started breastfeeding. However, this is not a guarantee as it can occur at different time in different women.

Pediatric Use

Safety and efficacy of Minastrin 24 Fe have been documented only in women who are 18 years and older (reproductive age). The result is said to be the same for all women under 18 but who have started experiencing the changes of puberty and adolescent. This medicine is not approved for used in women with no signs of puberty.

Geriatric Use

The safety and efficacy of the use of Minastrin 24 Fe in women who are 65 years of age and older has not been established, and thus, it’s not approved for used by subjects in this age group or postmenopausal women.

Renal Impairment

The rate at which Minastrin 24 is eliminated from the kidney has not been established in subjects with renal impairment.

Hepatic Impairment

The rate at which Minastrin 24 is eliminated or metabolized in the liver has not been established in subjects with hepatic (liver) impairment. However, steroid hormones are known to be poorly metabolized in subjects with hepatic impairment. Subjects with severe hepatic impairment should not be administered COC and it use may be immediately discontinue if patient is discover to develop severe disturbances of liver function. Minastrin 24 Fe use may only be reinstated and with caution if markers of liver function return to normal and its known not to be caused by COC.

Body Mass Index

The safety and efficacy of the use of Minastrin 24 Fe in women whose body mass index (BMI) is greater than 35 kg/m² has not been established.


Women who are 35 years and older, and taking this drug are advised not to take cigarette. Cigarette smoking women of this age range who are taking a combination oral contraceptive (COC) have been said to increases the potential risk of serious cardiovascular disorder. This risk is said to increase with age and proportional with the number of cigarettes smoked. Due to the need for safety, COCs is not approved and not recommended for use by women who consume cigarette and who are 35 years and older.

Blood Clothing disorders

You should immediately stop the use of Minastrin 24 Fe if an arterial or deep venous thrombotic event (VTE) takes place and also if there is an unexplained loss of diplopia, proptosis vision, retinal, or papilledema vascular lesions. You should go for an immediate retinal vein thrombosis examination. If you have been booked for surgery, you should stop taking this medicine at least 4 weeks before and through 2 weeks after major surgery, particularly surgeries known to have an increased risk of VTE. Also, you should not start taking the drug earlier of before 1 month after childbirth in women who are not involved in breastfeeding. The danger of postpartum VTE reduces after the third postpartum week, meanwhile the risk of ovulation accelerates after the third postpartum week.

The danger of VTE (venous thromboembolism) which is a blood clot that starts in a vein, multiplies with the use of COCs (Combined Oral Contraceptives). However, the danger of VTE arises as much or more than the application of COCs as a result of pregnancy. The danger of VTE in women applying COCs is three to nine per ten thousand women per year. The danger of VTE is at its highest point during the first year of use of a COC. After COC use is discontinued, the danger of thromboembolic disease as a result of oral contraceptives slowly fades away. Use of COCs also multiplies the danger of arterial thrombosis such as strokes and myocardial infarctions, most pertaining to women with other danger vectors for these events. COCs have been known to raise both the relative and attributable risks of cerebrovascular events (hemorrhagic strokes and thrombotic), even though, generally, the danger is most evident in older people less than 35 years of age) and hypertensive women who as well take tobacco. The danger of stroke in women with underlying risk factors, is equally increased by COCs. Use COCs with care and caution in women with cardiovascular disease risk factors like:

Liver Diseases

Women with delicate and sensitive viral hepatitis or severe (decomposition) cirrhosis of the liver should not be permitted to use Minastrin 24 Fe. Acute or chronic disruptions of liver function may demand or require the discontinuation of COC use until markers of liver function go back to normal and COC causation have been kept aside. Let the use of Minastrin 24 Fe be stopped if jaundice developed.

Also,Minastrin 24 Fe used is not allowed in women with benign and malignant liver tumors. Hepatic adenomas are in connection with COC use. It has been estimated that the connected danger of COCs subscribers is 3.3 cases per one hundred thousand. Death may be caused by a fusion of hepatic adenomas through intra-abdominal hemorrhage. Studies have revealed an increased risk of developing hepatocellular carcinoma in long-term greater than 8 years COC subscribers. However, the connected danger of liver cancers in COC subscribers or users is less than one case per million users.

Gallbladder disease

Studies suggest a small increased relative risk of developing gallbladder disease between COC subscribers. The application of COCs may equally amplify the already gall bladder ailment. A past account of COC-associated hot-temper predicts an increased risk with future COC use. Women with a history of pregnancy-associated hot-temper may be at an increased risk for COC-related hot-temper.

Carbohydrate and lipid metabolic effects

Pre-diabetic and diabetic women who are taking Minastrin 24 Fe should be carefully monitored. Glucose management may be decreased by COCs in a dose-related manner. Alternative contraceptive methods should be considered for women with uncontrolled supporter. A minute fraction of women will have unfavorable lipid changes while on COCs. Women who have a family history or longing could be at an increased danger of entering into when using COCs.

Unscheduled bleeding and spotting

Unprogrammed (breakthrough or intra-cyclic) bleeding as well as spotting take place sometimes in those affected by COCs,  especially during the first quarter use. If bleeding occurs or persists after past regular cycles, causes such as malignancy or pregnancy should be considered. If pregnancy and pathology are laid off, bleeding disorders may be handled over time or with a change to a different COC based on patient history.

Amenorrhea and oligomenorrhea

Amenorrhea (a condition in which there is an absence of menstrual periods in a woman) may be experienced by women who are not pregnant and who use Minastrin 24 Fe. Other women may also witness constraint (having light or infrequent menstrual periods) or post-pill amenorrhea, particularly when such a situation was pre-existent. If withdrawal (scheduled) bleeding does not manifest, consider the possibility of pregnancy. There is the probability that pregnancy would occur at the moment of the first missed period. This is possible if the person affected has not taken instruction to the ordered dose schedule (missed one or more active capsule or started taking them on a day later than she would have). In such a case, accurate diagnostic counseling should be given. If the patient has accepted to the ordered regimen and misses two non-stop periods, eliminate out pregnancy.

COC (Combined Oral Contraceptives) use before or during early pregnancy

Extensive epidemiologic studies have shown no increased risk of birth defects in women who have used oral contraceptives prior to pregnancy. Studies equally do not attempt termination impact, especially as cardiac anomalies and limb reduction defects are concerned, with oral contraceptives taken unknowingly during early pregnancy. If pregnancy has been confirmed, the use Minastrin 24 Fe should be stopped. Administration of oral contraceptives to induce withdrawal bleeding should not be used as a test for pregnancy.

Cancer of the breast and cervix

Minastrin 24 Fe is not approved for women who currently have or have had breast cancer because breast cancer may be hormonally-sensitive. There is great amount of proof that COCs do not multiply the incidence of breast cancer. Even though some previous studies have revealed that COCs might increase the incidence of breast cancer, more updated studies have not admitted such investigations. Other studies give suggestion that COCs are connected with an increase in the risk of cervical cancer or intraepithelial neoplasia. However, there is friction concerning the extent to which these findings may be due to differences in sexual behavior and other factors.

Effect on Binding Globulins

The estrogen component of COCs may step-up the serum concentrations of cortisol-binding globulin, sex hormone-binding and globulin thyroxine-binding globulin. Thus, the dose of replacing cortisol treatment or thyroid hormone may need to be stimulated.

Changing from one Hormonal Method of Contraception

If the patient is changing from a combination hormonal method, for example from another pill, vaginal ring, and patch, in such a situation, he should be advised to take the first yellow capsule on the day scheduled for her next COC pill. Once on COC pill, she should discontinue any other tablet from her previous birth manage pack, and should not miss any day between packs. If she does not experience a retrieving bleed, put off pregnancy before start taking Minastrin 24 Fe. But if she previously used a transdermal patch or vaginal ring, advise her to start applying Minastrin 24 Fe on the day she would have resumed the previous product.

If the patient changes from a progestin-only method such as a progestin-only pill, implant, intrauterine system, and the injection, she may switch any day from a progestin-only pill. The individual should be instructed to take the first yellow capsule on the day she would have taken her next progestin-only pill. She should apply a non-hormonal approach of contraception for 7 consecutive days. If switching from an injection or implant, begin the first yellow capsule on the day her next injection would have been due or on the day of removal of her implant. But if changing from an IUD, depending on the period of taking it off, back-up contraception may be required.

Customers Reviews of Minastrin 24 Fe

Very often, users give their feedback about medicines they have used. Some testified of their positive experience while others who are dissatisfied do testified such. Below are examples of some user’s reviews:

Positive Reviews

One who had extremely irregular periods, heavy and always with strong cramps that cause vomiting, breast tenderness, and headaches were totally gone with Minastrin. After Minastrin was administer according to doctor’s prescription, the period now only last 2 to 4 days, light and regular.

Negative Reviews

One mother reports of the death of her daughter from blood clot in the lungs in just a month following the initiation of Minastrin 24 Fe. The said daughter has no history of any condition that could increase the risk of any undesirable reaction such as smoking, or overweight.  Others report of increased depression, nausea, anxiety, headache, cramps, and irregular and heavy periods.

Note that, reviews from users are in no way a replacement for a doctor’s prescription or advice.

A Disclaimer: This article has been able to provide some useful tips and has given you ample insights on the Minastrin 24. However, what you should note is that this article only acts as a guide and should not replace doctor’s prescription.

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